The Clair I/O's are simply Lake Contours at heart. They're going for great prices on ebay, and I highly suggest them if you want a Lake at a good price.
This might be pushing the rules of the forum. But at eventually when you start getting larger than say 16 outputs id start looking at the PLM amplifiers. Using Dante one can look at 10 PLM10000Q amplifiers as a large matrix.
100,000 watts
20 inputs
40 outputs
The amplifier becomes a decentralized i.o.
Channels get routed to any in, any out.
Price wise things get very competitive when one considers that a centralized DSP (Audia/MediaMatrix/London) will not be required.