Re: Some thoughts on "mixing"
Jay,
I am thinking the same thing. It is my intention to get a variant of the X32 to mix with and to save scenes for different songs which I will switch via MIDI when live (I mix from stage).
Of course, this only works if the input gain on the channels remains constant from when you created the scene.
My bass player uses a DI exclusively, so no problem there. The drummer .... vDrums, so that should be pretty easy to get right. The microphones .... again, this should be the same as long as the mic's stay the same.
It's those darned guitars 
I sing lead and play rhythm. I dime my guitar and do all my tone changes through patches on my 2120. That is also where I get my boost for leads. Because of this, my volume is pretty consistent between patches and through the night (although sometimes my VHT amp does get a little louder as the night goes on as the tubes heat up). This is still pretty easy to get right.
It is the lead guitar player that is tough. He modifies his tone by rolling off or on the guitar volume knob. He has a chain of individual efx which get bumped from gig to gig when moved and thus sometimes simply engaging part of the chain changes the volume level.
My cure (more like a bandaid) for this is going to be to have an iPad / PC Tablet mounted on my microphone stand showing the input gains. If things get screwy, I can do a quick modification to either his gain, or his fader.
This isn't as good as having a dedicated sound man, but even the soundman would have issues with continual changes in volume. Sound would simply be better if guitar players would put a little thought into consistency 